AscellaOne™—A Better Way Forward

Pharmacy benefits are complex, but your business doesn’t have to be. AscellaOne™ is the first strategic enablement platform that brings payers and vendor partners together in a modular ecosystem, delivering the capabilities of a large, vertically integrated PBM—without being one.

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Welcome to Membership

Modern Pharmacy Benefits Built on Efficiency, Transparency, and Trust

Leveraging the power of a new group purchasing marketplace, AscellaOne membership unifies pharmacy access, financial optimization, and best-in-class technology into a single, enterprise-level solution.

Network Access Engine
100% specialty drug coverage through a large specialty pharmacy network plus convenient retail distribution coverage through a network of 65K+ retail pharmacies 
Specialty Pharmacy HUB
Cost-effective access and white glove patient journey management, including member and provider call center, and specialty and medical specialty fulfillment
Operational Support
Optimized patient financial assistance opportunities to keep member financial responsibility as affordable as possible
Formulary Discounts
Combined pharmacy and medical rebate management for cost-effective administration of complex specialty therapies
PBM Marketplace Services
Access to critical ancillary services to streamline pharmacy benefits execution (i.e. stop-loss insurance, call centers, etc.) with choice and transparency

Unlocking Value for the Entire Ecosystem

A Single Platform Serving All Pharmacy Benefits Stakeholders

Through aggregated purchasing power, modern technology, smarter benefit design, and high-touch specialty expertise, AscellaOne aligns incentives around value and restores confidence in how pharmacy benefits are delivered.

Employers, Brokers and TPAs

Achieve enterprise-level savings through group purchasing power and rebate transparency, without adding administrative burden or sacrificing flexibility.

PBMs and Health Plans

Accelerate total cost-of-care savings and enhance specialty performance while preserving autonomy, compliance and independence.

Rising to the Moment

New Therapies. Rising Costs. Intensified Scrutiny

This is the time to rethink everything.

11%+

Pharmacy Spend YoY¹

75%

New Specialty Drug Approvals²

23+

States with New Regulations³

52%

Employer Disruption⁴

Enabling Access and Affordability

A Proven Track Record of Innovation and Results

Built on a proven track record in high-cost specialty pharmacy, AscellaOne now offers a comprehensive solution for all aspects of pharmacy benefits that remains tightly aligned to our company values:

Innovation that Keeps Pace with the Market

From the earliest days of our company, we set out to build solutions that make a measurable difference for those struggling to navigate complex, often misunderstood conditions. That same mission guides the launch of AscellaOne, built specifically for the emerging realities of the modern healthcare landscape.

Value Creation through Aggregated Purchasing Power

Through aggregated purchasing power, modern technology, smarter benefit design, and high-touch specialty expertise, the AscellaOne platform aligns incentives around value which should lead to restored confidence in how pharmacy benefits are delivered.

Commitment to Patients and Partnerships

Built on experience, driven by compassion, and designed for what’s next, AscellaOne empowers payer organizations to move forward with greater confidence, control, and clarity. Together, the goal is to create a smarter, more sustainable path that improves access, affordability, and outcomes for the patients who need them most.

Offering Scale at Your Pace

Flexible Service Offerings to Meet Your Needs

Tackle your highest priorities and add additional components as your program grows, with flexible contracting structures to ensure you pay only for what you need.

Specialty Pharmacy Fulfillment
Includes access to all specialty medications, streamlined specialty drug distribution, and integrated specialty drug rebate management.
Medical Specialty Services
Includes comprehensive medical benefit support, infusion therapy site of care optimization, and enhanced medical specialty drug management.
Pharmacy Benefit Services
Includes complete pharmacy benefit administration, robust member and provider infrastructure support, and rebate and program coordination.

Lets Transform Healthcare—Together

At AscellaHealth, we believe that healthcare should work better for everyone—especially those who need it most. Through efficient management of high-cost therapies and hands-on care coordination, we help you lower costs while raising the standard of care.

Lets Transform Healthcare—Together

At AscellaHealth, we believe that healthcare should work better for everyone—especially those who need it most. Through efficient management of high-cost therapies and hands-on care coordination, we help you lower costs while raising the standard of care.

AscellaOne

Last updated Apr 2, 2026

¹Source: Understanding the Use of Medicines in the U.S. 2025
²Source: Build and improve pharmacy plan conversations with your clients using these key challenges
³Source: State Drug Transparency Laws — 2025 Update
Source: Build and improve pharmacy plan conversations with your clients using these key challenges