Finally, a Pharmacy Benefit Model Built Around Your Plan — Not Your Vendors.

AscellaHealth enables Health Plans to take back control of their pharmacy benefits. AscellaOne, a first-of-its-kind pharmacy benefits marketplace, enables the choice, transparency, control and compliance needed to manage drug costs without sacrificing member outcomes in today’s complex healthcare environment.

logo

You’re Accountable for Costs You Can’t See

Health plans are caught in an impossible position. Specialty drug spend is growing faster than any other cost category — accounting for nearly half of total pharmacy spend — yet most plans have limited visibility into what’s actually driving those costs. Add growing regulatory requirements under CAA 2026 and ERISA fiduciary standards, and the stakes of operating without a clear line of sight have never been higher. The legacy PBM model wasn’t designed for this environment. You need more than data. You need a partner who gives you control.

Our Services

A Modular Platform Built for
Health Plan Performance

AscellaOne’s marketplace-based approach gives health plans the access and flexibility to choose best-in-class capabilities — without the rigidity of a single bundled PBM arrangement.

Specialty Drug Cost Management

Transparent, competitive pricing, and access to all therapies, including LDD and exclusive distribution drugs.

Medical Benefit Specialty Management

Infusion therapy management and site-of-care optimization for high-cost medications administered under the medical benefit

Formulary & Utilization Management

Proven strategies to manage drug portfolios and sustain long-term savings

Pharmacy & Medical Benefit Rebate Optimization

Access to aggregated purchasing power and rebate strategies that improve yield without sacrificing access

Direct-to-Patient Specialty Fulfillment

Multi-accredited national specialty pharmacy network with 100% access to specialty medications, including limited distribution drugs

Compliance & Reporting Support

Data infrastructure and reporting designed to meet CAA 2026 and fiduciary requirements

What Makes Us Different

We Are Not A PBM, But A Partner Who 
Gives You The Power Of One

AscellaOne was built to give health plans access to capabilities that have historically only been available to the largest national plans — without the lock-in.

A Trusted Strategic Partner

We work alongside your team to navigate regulatory change, evaluate new therapies, and continuously improve plan performance.

Modular & Configurable

Replace underperforming components without disrupting your entire benefits structure. Adapt as the market changes.

Transparency by Design

Every component is visible and measurable — so you always know what you’re paying for and why.

Integrated Data Intelligence

Real-time, self-service data across claims, pharmacy, and financial data — not quarterly summaries after decisions have already been made.

Patient-Centered Execution

Cost control and member experience aren’t in conflict. Our clinical coordination model keeps patients on therapy while managing total cost.

Ready to See What’s Possible for Your Plan?

Whether you’re looking to reduce specialty drug spend, meet new compliance requirements, or simply get better visibility into your entire pharmacy benefit economics — AscellaHealth can help you build a smarter path forward.

Ready to See What’s Possible for Your Plan?

Whether you’re looking to reduce specialty drug spend, meet new compliance requirements, or simply get better visibility into your entire pharmacy benefit economics — AscellaHealth can help you build a smarter path forward.